4 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... have fever - ACS ... organ damage • Treatment ... acid, Elevated Cr ... #diagnosis #management
Cardiac Standstill on POCUS during CPR

A 79yo male presents after being found unresponsive by his wife.
on POCUS during CPR ... ACLS performed x ... few seconds of CPR ... activity p 30min ACLS ... #ACLS #S4C #Intraarrest
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... 5 or elevated Cr ... common • Imaging: CXR ... APML #diagnosis #management
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
fever: - Fever + ANC ... TLS (tumor-lysis ... interventional radiology ... - Occurs after CAR-T ... speech changes (CAR-T