24 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • recurrent fractures ... adult population: also ... mineralization Symptoms ... pain - Frequent fractures
Diplopia - Double Vision - Differential Diagnosis Algorithm
Clinical Pearls:
 • Diplopia is almost always binocular.
 •
Algorithm Clinical ... • Neurologic symptoms ... suggest a mass as ... Orbital Floor Fracture ... #Algorithm #Causes
Lisfranc injury (tarsometatarsal fracture dislcoation)
 - 
Lisfranc injury can range from purely soft tissue injury to
tarsometatarsal fracture ... tissue injury to fracutre ... ) - diagnosis usually ... Dislocation #XRay #Foot ... #Clinical
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs/symptoms ... Autoimmune (SLE/APLS ... in up to 30% of cases ... common, Aortic root ... #Endocarditis #comparison
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pathogenesis and clinical ... Greater Trochanter Fracture ... pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... body, but can also ... Differential Diagnosis ... Malignancies (eg CML, ALL ... #oncology #diagnosis
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and clinical associations ... and duration of symptoms ... doi: 10.1111/all ... #rheumatology #comparison
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... ) Summary ALS: combination ... (1) limb-onset ALS ... ) bulbar-onset ALS ... fasciculations Common Symptoms
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... & Fe Sucrose > alt ... diet/deficiency symptoms ... /other causes • ... #diagnosis #management
Restrictive Cardiomyopathy - Diagnosis and Causes
Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema)
Physical
Cardiomyopathy - Diagnosis ... and Causes Clinical ... ↑ "Right Sided-Symptoms ... : Amyloidosis (AL ... #cardiology #algorithm