7 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced ... Liver Injury (DILI ... Chronic - ongoing ↑ LFTs ... #Drug #induced ... #Liver #Injury #
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Injury (DILI) - ... exposure to HDS, drugs ... non-essential drug ... #Algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... (>1000): • DILI ... (Drug-induced liver ... injury) • Ischemic ... Function #Tests #LFTs
Differential Diagnosis of Hypoglycemia
Evaluation of Hypoglycemia
Patients with known diabetes who are not systemically ill and can
of Hypoglycemia Evaluation ... consider: - BMP - LFT ... #Differential #Algorithm ... #Drugs #Malignancy ... #Hypoglycemic #Ddxof
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Diagnosis and Evaluation ... history (cardiac, liver ... renal disease), drug ... history #Diagnosis #EM ... #Ddxof
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... bilirubin (Conjugated/DBili ... hepatocellular injury ... impaired uptake (drugs ... Function #Tests #LFTs
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injuryliver ... valproate, azoles), Drugs ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis