21 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... glucocorticoid treatment ... organ-specific signs ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of hip (rare), Arthritis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... , Arthritis, myalgia ... • Treatment: ... #comparison #table ... diagnosis #management
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... myositis, and arthritis ... Can also see mechanics ... after 2 years of treatment ... #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Diagnosis Framework ... - SLE - Behcet ... Intra-articulation fracture ... #diagnosis #msk
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Manifestations: - Arthritis ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behcet disease) Differential ... : SLE, Reactive ... Arthritis, AS Treatment ... #management #signs ... #symptoms #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
or nerve root Symptoms ... #Joint #Pain #MSK ... approach #workup ... #differential # ... diagnosis #arthritis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... #Diagnosis #MSK ... #rheumatology #
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... Treatment of GCA ... GCA #Temporal #Signs ... #Symptoms #Diagnosis