41 results
Hepatitis B Management in Cancer

DOI: 10.1200/JCO.20.01757

#HepatitisB #HBV #HepBV #Management #Cancer #oncology #hepatology #algorithm
Hepatitis B Management ... in Cancer DOI: ... HepatitisB #HBV #HepBV #Management ... #Cancer #oncology ... #hepatology #algorithm
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Decreased ENaC channel function ... Aldosterone Release: ACE inhibitors ... Aldosterone Receptor Function ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... inducers (↑) and inhibitors ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Atopic Dermatitis - Topical Treatment Options 
First Line: Topical Corticosteroids 
  - High Potency: Betamethasone
Topical Calcineurin Inhibitors ... therapy is non-pharmacologic ... the first line pharmacologic ... #Medications #Pharmacology ... #Dermatology #Management
Atopic Dermatitis - Topical Treatment Options 
First Line: Topical Corticosteroids 
  - High Potency: Betamethasone
Topical Calcineurin Inhibitors ... After non-pharmacologic ... a topical PDE4 inhibitor ... #Medications #Pharmacology ... #Dermatology #Management
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... has very minimal chance ... check the kidney function ... Renal #Dosing #Pharmacology ... #Management #Diabetes
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... BetaBlockers #Cirrhosis #hepatology ... #management #pharmacology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... heparin (UFH): Inhibits ... the function of ... heparin (LMWH): Functions ... #Pharmacology #Pathophysiology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
the treatment of cancer-associated ... trial evidence in cancer-associated ... VTE #Malignancy #Cancer ... Anticoagulation #Management ... #Hematology #Oncology
Checkpoint inhibitors and indications
Anti CTLA-4 antibody:
 • Ipilimumab: Malignant melanoma, Renal cell cancer
Anti-PD-1 antibody:
 • Nivolumab:
Checkpoint inhibitors ... , Gastric cancer ... #Checkpoint #inhibitors ... #indications #oncology ... #pharmacology