17 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Decreased ENaC channel function ... Aldosterone Receptor Function ... Tacrolimus - Amelia ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
Alexia without ... gyrus (the reading center ... Pathophysiology: ... Agraphia #clinical #neurology ... #diagnosis #pathophysiology
Causes of Urinary Tract Obstruction - Differential Diagnosis Algorithm
Upper Tract - Bladder NOT distended on ultrasound,
Fibrosis • Cancer ... Ureteropelvic junction ... • Prostate cancer ... Algorithm #Causes #Urology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Nephron and their Functions ... Nephron #Segments #Function ... #Pathophysiology ... #Tubules #Table ... #Pharmacology
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
normal kidney function ... it's more of a concern ... ACEIARB #Effects #Nephrology ... #Renal #Pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Dose-dependent tremor, ataxia ... , asthenia • Neurologic ... dizziness, diplopia, ataxia ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Priapism: Pathogenesis

 - Post-cavernosal venous occlusion -> Post-cavernosal venous drainage is mechanically obstructed e.g. sickle cell
Inadequate venous function ... #Priapism #Pathophysiology ... #Urology #Diagnosis
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
of breath • Neurologic ... decline in mental function ... #emergencies #oncology ... differential #diagnosis #cancer
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Interactions #Table ... #Pharmacology
Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
inhibition of spinal center ... Erectile Dysfunction Neurologic ... #Dysfunction #Pathophysiology ... #Urology #Diagnosis