14 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair Renal ... Decreased ENaC channel function ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium #Renal
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
potassium, and renal ... function. ... Dosing #Conversion #Pharmacology ... PrimaryCare #Comparison #Table
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
normal kidney function ... it's more of a concern ... Effects #Nephrology #Renal ... #Pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Nephron and their Functions ... Nephron #Segments #Function ... #Pathophysiology ... #Tubules #Table ... #Pharmacology
Checkpoint inhibitors and indications
Anti CTLA-4 antibody:
 • Ipilimumab: Malignant melanoma, Renal cell cancer
Anti-PD-1 antibody:
 • Nivolumab:
Malignant melanoma, Renal ... , Renal cell cancer ... cell carcinoma renal ... #indications #oncology ... #pharmacology
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
patients with good renal ... function. ... Anticoagulation #Pharmacology ... #Table
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Inhibitors - Normal and Renal ... has very minimal chance ... patients have renal ... check the kidney function ... #Dosing #Pharmacology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Hyperuricemia • Acute renal ... decline in mental function ... #emergencies #oncology ... differential #diagnosis #cancer
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Interactions #Table ... #Pharmacology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Etiology ... Lung Abscess Pathophysiology ... antibiotics once stable ... shows a small, stable ... foreign body, cancer