17 results
Who to test for BRCA 1/2?
Female Breast Cancer:
 • ≤ 45-50 years at diagnosis
 • Triple
Female Breast Cancer ... in this table ... factors in this table ... Jewish adults - BWH ... #indications #oncology
Causes of Urinary Tract Obstruction - Differential Diagnosis Algorithm
Upper Tract - Bladder NOT distended on ultrasound,
Fibrosis • Cancer ... Ureteropelvic junction ... Tract • BPH ... • Prostate cancer ... Algorithm #Causes #Urology
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
pre-dose (trough) BP ... Monitor BP, potassium ... , and renal function ... Dosing #Conversion #Pharmacology ... PrimaryCare #Comparison #Table
Summary of meta-analysis of pharmacotherapy trials in BPD
https://www.cochrane.org/CD005652/BEHAV_psychological-therapies-borderline-personality-disorder
Meta-analyses of RCTs were undertaken for the following outcomes:
psychopathology, anger ... summarised in Tables ... EBM #Management #Pharmacology ... #BPD #Borderline ... Effectiveness #Table
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Nephron and their Functions ... Nephron #Segments #Function ... #Pathophysiology ... #Tubules #Table ... #Pharmacology
Priapism: Pathogenesis

 - Post-cavernosal venous occlusion -> Post-cavernosal venous drainage is mechanically obstructed e.g. sickle cell
Inadequate venous function ... #Priapism #Pathophysiology ... #Urology #Diagnosis
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
inflammation #BPH ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology ... #Urology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
tumour, stone, BPH ... Incontinence #Mixed #Pathophysiology ... Signs #Symptoms #Urology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Interactions #Table ... #Pharmacology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
catheterization • BPH ... • Prostate cancer ... Diagnosis #causes #urology