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diagnosis betadglucan galactomannan infectiousdiseases pulmonary treatment abscess arteritis aspergillus biomarkers causes chest coccidioidomycosis comparison ct cxr disease eosinophilia eosinophils falsepositives
Miliary Pattern - Chest Radiology • Miliary opacities are scattered, small (1 -4 mm) nodules •
throughout the lungs ... Opacities: • Infectious ... - Endemic fungi ... Nocardia, zoonotic infections ... pulmonary #CXR #clinical
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... Diaqnoses: • Infectious ... Prunelle Getten #AdultOnset ... #treatment #rheumatology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
component of many fungi ... infection (IFI) ... cut-offs defined in clinical ... BAL GM does not differentiate ... closely related fungi
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Summary Lung ... polymicrobial infection ... Lung Abscess - Clinical ... Prevotella • Fungal ... Abscess Differential
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
component of many fungi ... surfaces, Albumin, Infections ... in BAL does not differentiate ... result in + as long ... closely related fungi
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... has five major clinical ... stain of clinical ... change in the lungs ... #Diagnosis #Management
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Diagnosis and Management ... than 1500 and clinical ... hypersensitivity - Infection ... : helminthic, fungal ... #differential #
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
Diagnosis and Management ... Summary WHAT ... hypothyroidism, infection ... normal and can help differentiate ... #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... very remarkable w/differential ... vasculitis vs infection ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Coccidioidomycosis (Valley Fever) - Diagnosis and Management Summary WHAT? • Coccidioidomycosis due to Coccidioides immitis or Coccidioides
Diagnosis and Management ... Summary WHAT ... valley fever, is a fungal ... spherules in the lungs ... TREATMENT: Clinically
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