1501 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Maintenance: 10 g ... intervals in 5-g ... QoD to 15 g QD ... of aspiration #Potassium
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
) MECHANISM: Potassium ... DOSING: 8.4 g ... Increase by 8.4 g ... week, up to 25.2 g ... patiromer) is a potassium
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... ratio < 15 mEq/g ... ratio > 15 mEq/g ... #differential #potassium
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
protein ≤ 2.5 g/ ... protein ≥ 2.5 g/ ... albumin #gradient #hepatology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
pernicious anemia) • G-CSF ... nephrology #low #potassium
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
injury (≥ 1B) - 1 g/ ... days then 20-40 g/ ... Cirrhosis #treatment #hepatology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... K+ <13 mEq K+/g ... K+ >13 mEq K+/g ... hypokalemia #urine #potassium
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Platelets < 30 G/ ... management #treatment #rheumatology ... #hematology
Checklist Approach to Hypokalemia

Consider risk factors for arrhythmia:
 - EKG changes (especially QT prolongation)
 - Digoxin
safely, whereas potassium ... Consider target potassium ... Enteral potassium ... function & estimated potassiurn ... Intravenous potassium
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Infiltration: • Hematologic ... and non-hematologic ... Algorithm #Causes #Hematology