9 results
diagnosis hematology hemophagocytic hlh lymphohistiocytosis oncology apml causes chronic differentiation erythematosus gravis hemeonc idiopathic leukemia lupus lymphocytic lymphocytopenia lymphopenia myasthenia
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
(ICL) / Lymphocytopenia ... DIAGNOSTIC CRITERIA FOR ICL ... Autoimmune (Sjogren, SLE ... #Lymphopenia #ICL ... #Differential #
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... Autoimmune diseases: SLE ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... non-Hodgkin lymphoma SLL ... weeks without infection ... surface molecules: CD5 ... microglobulin Treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (SCLE ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... La, anti-Jo-1, SCL
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... initiation • Differential ... Diagnosis: Infection ... APML #diagnosis #management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... life-threatening Differential ... : - Bedside: ice ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
Diagnosis and Management ... Summary WHAT ... hypothyroidism, infection ... normal and can help differentiate ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Triggers: ▪ Infections ... of NK cells and CD8 ... underlying trigger: Infections ... #Hematology #HemeOnc
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
erythematosus (SLE ... with interleukin (IL ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management ... #rheumatology #
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