14 results
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Leukemia (CLL) - Summary ... Complications: 1) Infection ... transformation) Treatment ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary ... non-Hodgkin lymphoma SLL ... weeks without infection ... microglobulin Treatment ... Transform to DLBCL, PML
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... Summary Trauma ... Statins), ETOH Infection ... #treatment
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
mL or 20% total lymphocyte ... Autoimmune (Sjogren, SLE ... myelodysplasia) • Infections ... #diagnosis #hematology ... #Differential #
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Summary Lung ... polymicrobial infection ... Clindamycin in case of PCN ... Lung Abscess Differential ... Abscess #pulmonary #differential
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
rheumatoid arthritis, SLE ... life-threatening Differential ... Miller Fischer and PCB ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... Histoplasmosis Treatment ... count (mainly lymphocytes ... throat, skin, scalp ... Fungal #Diagnosis #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... Diagnosis: Infection ... fluid overload, PCC ... APML #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (SCLE ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... La, anti-Jo-1, SCL