13 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
is rare in DIL, SCLE-DIL ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Diagnosis and Management ... Epidemiology: • #1 ... non-toxigenic • Stool PCR ... (IDSA 2021): ... 10 mg/kg IV x 1
Capnocytophaga
Pathogen: Capnocytophaga
 • 9 species, C. canimorsus responsible for the majority of infections
 • Gram-negative rod,
the majority of infections ... ), Malignancy, SLE ... Incubation period is 1- ... infectiousdiseases #diagnosis #management ... #treatment
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
rheumatoid arthritis, SLE ... weakness in: 1. ... EMG Findings: 1. ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (SCLE ... Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... symptoms, or> 1 ... Differential Diagnosis: Infection ... fluid overload, PCC ... APML #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
cytokines, such as IL-1 ... erythematosus [SLE ... ], AOSD) • Infection ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... weeks without infection ... CLL Labs: 1. ... microglobulin Treatment ... Transform to DLBCL, PML
IDSA Recommendations for Prevention and Treatment of Pneumocystis Pneumonia (PCP) in HIV-AIDS
Indications for Initiating Primary Prophylaxis:
IDSA Recommendations ... Prevention and Treatment ... #Prevention #Treatment ... opportunistic #infections ... #HIVAIDS #management
IDSA Recommendations for Preventing and Treating Cryptococcosis in HIV-AIDS
Treatment for cryptococcosis consists of 3 phases: induction,
IDSA Recommendations ... PO for at least 1 ... year (AI)—see below ... #management #opportunistic ... #infections #HIVAIDS