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diagnosis differential hematology nephrology nephrotic syndrome hematuria acute aki disorders hemolytic management nephritic pancytopenia proteinuria syndromes treatment urology aafp antiphospholipid
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... and Diagnosis Algorithm ... mimics, repeat testing ... • Evidence of glomerular ... Nephrology if cause
Causes of Hematuria - Glomerular vs Non-glomerular == Glomerular == - Glomerulonephritis - Thin basement membrane disease ==
- Glomerular vs ... Non-glomerular ... == Glomerular ... disease == Non-glomerular ... #Algorithm #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... present on repeat testing ... including overnight testing ... • Drugs Glomerular
Causes of Acute Kidney Injury - Differential Diagnosis Framework Pre-Renal Post-Renal Intrinsic Renal: • Tubules (ATN) • Glomerular:
Causes of Acute ... Tubules (ATN) • Glomerular ... #KidneyInjury #Causes ... Differential #Diagnosis #Algorithm
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... • Calculi Glomerular ... epithelial side of glomerular ... endothelial side of glomerular
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic Algorithm ... and Causes Increased ... Hemolysis #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... monitoring low-level glomerular ... of glomerular disease ... disorders #glomerular ... #testing #workup
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
INTRINSIC: - Glomerular ... or pigmented casts ... nephrotoxic drugs, treating ... underlying cause ... percutaneous drainage, or stenting
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
the patient have glomerular ... hematuria (RBC casts ... Syndrome #Comparison #Algorithm
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... monitoring low-level glomerular ... of glomerular disease ... #glomerular #disease ... #workup #diagnosis
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