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diagnosis management differential clinical hematology treatment nephrology cardiology causes hepatology radiology criticalcare syndrome workup dermatology microscopy oncology acute comparison msk
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
overt cytoplasmic granules ... , and Auer rods. ... features in most ... cases, even the ... promyelocytic #leukemia #APL
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... decreased secondary granules ... In addition to APL ... , Auer rods in neutrophils ... Rods #AuerRods #APL
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 Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
a linear red "Auer ... of crystallized granules ... most prevalent in ... Smear #Microscopy #Auer ... Rods #AuerRods #AML
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... sterile pyuria, WBC casts ... tubular proteinuria, granular ... casts/RTE; blend ... #Algorithm #nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Acellular Casts ... but can be seen in ... tubular necrosis (ATN ... Non-specific; seen in ... ) • Granular Casts
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... nonspecific; seen in ... concentrated urine Granular ... Muddy-brown" heme-granular ... in acute tubular
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
from anywhere in ... = inflammation in ... renal disease • Granular ... • “Muddy brown cast ... crystals can be found in
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... leukemias > 20% blasts in ... infections, bone pain ... Age: 50-60 • Auer ... distinctive primary granules
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... Acute • Myloid (AML ... , Sudan Black, Auer ... • Lymphoid (ALL ... Differential #Diagnosis #Algorithm
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
hematuria (RBC casts ... dysmorphic RBCs in ... Syndrome #Comparison #Algorithm
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