9 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
overt cytoplasmic granules ... , and Auer rods. ... features in most cases ... KyleBradleyMD #Auer ... #APML #Pathology
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
a linear red "Auer ... rod" composed of ... crystallized granules ... Smear #Microscopy #Auer ... #Rods #AuerRods
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... rods. ... decreased secondary granules ... rods. ... , Auer rods in neutrophils
Auer Rods - Bone marrow aspiration revealed 5% blasts and 65% promyelocytes; many promyelocytes had prominent
Auer Rods - Bone ... had prominent Auer ... rods (arrows) and ... Clinical #Path #APL ... #AuerRods #Auer
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach ... sterile pyuria, WBC casts ... tubular proteinuria, granular ... casts/RTE; blend ... Nephritis #AIN #Algorithm
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... Acute • Myloid (AML ... , Sudan Black, Auer ... rod • Lymphoid ... Differential #Diagnosis #Algorithm
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... Age: 50-60 • Auer ... Rods Significant ... smear: Blasts APML ... distinctive primary granules
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Scl70 (in some cases ... Scl-70 (in some cases ... conditions - Sp-100, PML ... golgin-245 • Rods
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... transformation into MDS or AML ... • Treatment algorithms