29 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Clinical Presentation ... anemia • Cold ... younger pts) Differential ... Test: Donath-Landsteiner ... test #cold #
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... to right with bands ... likelihood of negative clinical ... #differential # ... CBC #hematology #pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
clinical findings ... clumsiness in hands ... #Acute #SpinalCord ... #pathophysiology ... #signs #symptoms
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Diagnosis Framework ... should be based on clinical ... Antimicrobial treatment ... #differential #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... (GI symptoms/endemic ... (CVID, WAS), (neurologic ... changes), high MCV anemia
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Neurocognitive Disorder (HAND ... • Depressive symptoms ... Diagnosis: MRI ... reversible • HAND ... HIV patients #HAND
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
and treatment can ... clinical consistent ... BEE #Syndromes #neurology ... noninflammatory #differential ... #diagnosis
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Diagnosis Framework ... neurological lesion: Clinical ... Infections: - ... #spinal #cord #spinalcord ... #neurology #differential
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... Diagnosis: • ... T2 Treatment ... #diagnosis #causes ... #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Bedside: ice pack test ... /Edrophonium test ... precipitated by: Drugs, infection ... #management #neurology