13 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... Lysis Syndrome ... Leukostasis: • ... Medicine @SCVMCMed #Leukostasis ... #management #hematology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... Initial workup ... #Syndrome #diagnosis ... #management #oncology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Hyperviscosity Syndrome ... Leukostasis: • ... Superior Vena Cava Syndrome ... EMERGENCIES: Tumor Lysis ... Syndrome: • Azotemia
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... wandering_er #Tumor #Lysis ... #Syndrome #TLS ... #oncology #management
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... #TumorLysis #Syndrome ... TLS #diagnosis #management ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... Myelodysplastic #Syndrome ... #treatment #hematology ... #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... full infectious work-up ... days → add fungal work-up ... TLS (tumor-lysis ... anticoagulation Leukostasis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
↑ Can develop leukostasis ... syndrome: CNS manifestations ... & DIC • Tumor lysis ... syndrome: Develops ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Richter’s Syndrome ... leukemia • Sezary syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management