258 results
Rheumatoid arthritis (RA): X-ray features
 • Soft tissue swelling (best seen by comparing left & right
Narrowing • Bony ... the articular bone ... Peri-articular osteopenia (bones ... Diagnosis #Radiology #Clinical ... #Pathophysiology
Representative X-ray appearance of a primary benign bone tumor - Aneurysmal Bone Cyst 
 • Soft
primary benign bone ... tumor - Aneurysmal Bone ... the articular bone ... Peri-articular osteopenia (bones ... ShoulderXRay #Radiology #Clinical
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
signs, Fragile bones ... easily/weakness, Bone ... Secondary #Tertiary #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver, bone ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... Skeletal: - Bone
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... resorption in the bone ... resorption in the bone ... Hypercalcemia #Malignancy #Pathophysiology ... Differential #Diagnosis #algorithm
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Pathogenesis and clinical ... mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Differential Diagnosis Algorithm ... production: • Bone ... suppression • Bone ... marrow failure • Bone ... Differential #Diagnosis #Algorithm
Representative X-ray appearance of a primary malignant bone tumor - Ewings Sarcoma
 • "Interrupted periosteal reaction
primary malignant bone ... Moth-eaten", permeative bone ... transition between bone ... accumulation around the bone ... Sarcoma #Radiology #Clinical
Pancytopenia - Differential Algorithm / Schema

- Bone Marrow Failure
- Bone Marrow Infiltration
- Sequestration / Destruction

#Pancytopenia #Differential
- Differential Algorithm ... / Schema - Bone ... Marrow Failure - Bone ... #Differential #Algorithm
Hypercalcemia - Hormones and Pathophysiology  
Calcitriol:
 • Bones: Enhances mineralization
 • GI Tract: ↑ Ca2+
Calcitriol: • Bones ... PO4- PTH: • Bones ... : ↑ Bone resorption ... Calcitonin: • Bones ... : ↓ Bone resorption