79 results
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
excessive bone ... turnover -> Incr bone ... Incr (abnormal) bone ... MSK • Deformed bones ... PagetsDisease #pathophysiology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic Algorithm ... and Causes Increased ... hyperplasia of bone ... #Differential #Causes ... #Workup #Hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... other orthopedic complications ... BrighamChiefs #Bone ... differential #diagnosis #causes
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Differential Diagnosis Algorithm ... Flow cytometry, Bone ... Alcoholism Bone ... • Congenital bone
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the ... of Sickle Cell Crises ... Hematology #SickleCell #Complications ... Manifestations #Workup ... #Algorithm #Ddxof
Amyloidosis - Workup and Diagnostic Algorithm
 • Serum Immunofixation and Serum Free Light Chains
 • Biopsy
Amyloidosis - Workup ... and Diagnostic Algorithm ... skin, fat pad, bone ... chain ratio • Bone ... #Amyloidosis #Workup
Malignant Bone Tumors: Clinical Findings and Complications

#Malignant #BoneTumors #Bony #Complications #pathophysiology
Malignant Bone Tumors ... Clinical Findings and Complications ... Malignant #BoneTumors #Bony ... #Complications ... #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver, bone ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... Skeletal: - Bone
Bone Lesion on X-Ray - Differential Diagnosis Algorithm 
Exostotic
 • Osteochondroma
Asymptomatic &/or Non-Active Bone Scam
 •
Bone Lesion on X-Ray ... /or Non-Active Bone ... • Unicameral Bone ... • Aneurysmal Bone ... #Orthopedics #Causes
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Differential Diagnosis Algorithm ... Flow cytometry, Bone ... Alcoholism Bone ... • Congenital bone