107 results
Paget's Disease of Bone

 • Characterized by an ↑ rate of bone turnover with both excessive
Paget's Disease of Bone ... by an ↑ rate of bone ... and formation of bone ... Pagets #Disease #Bone ... #diagnosis #management
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
hyperCalcemia 28% (bone ... • Anemia 78% (bone ... macrocytic • Bone ... Diagnosis - Clonal bone ... clonal cell in bone
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Flow cytometry, Bone ... Alcoholism Bone ... • Congenital bone ... #Pancytopenia #Workup
Amyloidosis - Workup and Diagnostic Algorithm
 • Serum Immunofixation and Serum Free Light Chains
 • Biopsy
Amyloidosis - Workup ... skin, fat pad, bone ... chain ratio • Bone ... #Amyloidosis #Workup
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Flow cytometry, Bone ... Alcoholism Bone ... • Congenital bone ... #Pancytopenia #Workup
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... swelling of the bone ... • Bone and joint ... as the collar bone ... Rheumatology #diagnosis #management
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
deficiency - Probable bone ... #differential #workup
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
hyperplasia of bone ... Differential #Causes #Workup
Hypocalcemia Workup - Differential Diagnosis Algorithm
 • Low Magnesium, High Magnesium - Functional Hypoparathyroidism
 • High
Hypocalcemia Workup ... metastases, Hungry bone ... #Hypocalcemia #Workup
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Diagnosis and Management ... - Accelerated Bone ... Formation: Hungy Bone ... Hypocalcemia #Diagnosis #Management