28 results
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated ... Light chain: - HHV8 ... + Multicentric Castleman ... de Fremont #HHV8 ... comparison #diagnosis #kshv
KSHV Inflammatory Cytokine Syndrome (KICS)
Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV Inflammatory ... 3) Evidence of KSHV ... activity - Elevated KSHV ... Castleman disease ... diagnosis #management #hhv8
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
Castleman's Disease ... • unicentric, HHV8 ... associated with Castleman's ... Plasmablastic subtype is HHV8 ... myeloma, POEMS) HHV8
Kaposi Sarcoma Herpes Virus (KSHV)

By Dr. Sara Dong @swinndong via #IDFellowCase
#ID  #Infectious Diseases  #Infections
#Differential
Herpes Virus (KSHV ... Ddx #Diagnosis #KSHV ... #HHV #lymphoproliferative
KSHV Inflammatory Cytokine Syndrome (KICS)

By Dr. Sara Dong @swinndong  via #IDFellowCase
#ID  #Infectious Diseases
KSHV Inflammatory ... Ddx #Diagnosis #KSHV ... #HHV #KICS #Kaposi
Pathology - Castleman disease. 

Mediastinal mass in a younger woman.

Histologic Features of Castleman disease, hyaline vascular
Pathology - Castleman ... Histologic Features of Castleman ... @mjcascio #Castleman
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Herpes Viruses (HHV ... herpes virus 6 HHV ... herpes virus 7 HHV ... herpesvirus 8 HHV ... Herpes #Viruses #HHV
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
Preventing and Treating HHV ... , Multicentric Castleman ... activity against HHV ... adjunctive therapy #HHV8 ... KaposiSarcoma #Castlemans
Lymphadenopathy - Differential Diagnosis Algorithm
Localized: 
 • Cervical: EBV, CMV, HIV, Toxo, TB, Lymphoma, Head /
Miscellaneous: Castleman's
IgG4-associated conditions

Diagnosis of IgG4 disease is depending on BIOPSY. While IgG4 levels can be informative (and
polyangiitis, and Castleman