2648 results
Kaposi Sarcoma Herpes Virus (KSHV)

By Dr. Sara Dong @swinndong via #IDFellowCase
#ID  #Infectious Diseases  #Infections
#Differential
IDFellowCase #ID #Infectious ... Diseases #Infections ... Diagnosis #KSHV #HHV
KSHV Inflammatory Cytokine Syndrome (KICS)

By Dr. Sara Dong @swinndong  via #IDFellowCase
#ID  #Infectious Diseases
IDFellowCase #ID #Infectious ... Diseases #Infections ... Diagnosis #KSHV #HHV
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Herpes Viruses (HHV ... 20%) congenital infection ... Mononucleosis-like disease ... herpes virus 6 HHV ... herpes virus 7 HHV
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Virus (EBV, CMV, HHV8 ... • Autoimmune diseases ... Adult-onset Still disease ... , Infection under
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
Preventing and Treating HHV ... -8 Diseases—Kaposi ... activity against HHV ... adjunctive therapy #HHV8 ... opportunistic #infections
KSHV Inflammatory Cytokine Syndrome (KICS)
Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV-multicentric Castleman disease ... if present Infectious ... Diseases Fellows ... diagnosis #management #hhv8
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
to an existing infection ... worsening of that disease ... opportunistic infection ... pericarditis, peritoneal disease ... Kaposi sarcoma, HHV8
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
Castleman's Disease ... • unicentric, HHV8 ... with Castleman's disease ... Plasmablastic subtype is HHV8 ... myeloma, POEMS) HHV8
Radiographic appearances of pulmonary disease in HIV-infected patients

By Dr. Sara Dong @swinndong via #IDFellowCase

#ID  #Infectious
appearances of pulmonary disease ... IDFellowCase #ID #Infectious ... Diseases #Infections
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated ... diseases: From ... Light chain: - HHV8 ... de Fremont #HHV8 ... #diseases #comparison