13 results
Kaposi Sarcoma Herpes Virus (KSHV)

By Dr. Sara Dong @swinndong via #IDFellowCase
#ID  #Infectious Diseases  #Infections
#Differential
Kaposi Sarcoma Herpes ... swinndong via #IDFellowCase ... Diagnosis #KSHV #HHV
KSHV Inflammatory Cytokine Syndrome (KICS)

By Dr. Sara Dong @swinndong  via #IDFellowCase
#ID  #Infectious Diseases
swinndong via #IDFellowCase ... Diagnosis #KSHV #HHV ... #KICS #Kaposi
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated ... Hyperinflammation Kaposi ... Light chain: - HHV8 ... de Fremont #HHV8 ... diagnosis #kshv #kaposi
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Herpes Viruses (HHV ... subclinical (80-90%) Oral ... herpes virus 6 HHV ... herpes virus 7 HHV ... herpesvirus 8 HHV
Kaposi’s Sarcoma of the Oral Cavity - Physical examination revealed multiple, firm, nontender, violaceous plaques of
Kaposi’s Sarcoma ... of the Oral Cavity ... Clinical #HONC #Kaposi ... Kaposisarcoma #Oral
Oral Cavity Lesions in a patient with HIV/AIDS
White plaque
 - Pseudo-membranous candidiasis
 - Oral hairy leukoplakia
Oral Cavity Lesions ... candidiasis - Oral ... Wart (HPV) - Kaposi's ... Darcy_ID_doc #Oral
Infection-Related Cancers
Viruses:
 • HPV - Cervical, anogenital, head and neck, skin cancer
 • HTLV-1 - Adult
• HIV - NHL, Kaposi's ... Hepatocellular carcinoma • HHV ... -8 - Kaposi's sarcoma
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
Streptococci (oral ... reactivation), HHV
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
Preventing and Treating HHV ... -8 Diseases—Kaposi ... activity against HHV ... specialist) + ART • Oral ... adjunctive therapy #HHV8
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Kaposi sarcoma ... , HHV8 - Worsening