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Clinical Manifestations of Human Herpes Viruses (HHV) Herpes simplex virus 1 HSV-1 Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Clinical Manifestations ... Herpes Viruses (HHV ... 20%) congenital infection ... herpes virus 6 HHV ... herpes virus 7 HHV
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... accumulation of clinical ... Assessment • Clinical ... Virus (EBV, CMV, HHV8 ... Still disease, Infection
KSHV Inflammatory Cytokine Syndrome (KICS) Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
Requires at least 2 clinical ... 3, and 4. 1) Clinical ... if present Infectious ... diagnosis #management #hhv8
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
to an existing infection ... opportunistic infection ... noncompliance • Clinical ... initiation Clinical ... Kaposi sarcoma, HHV8
Kaposi Sarcoma Herpes Virus (KSHV) By Dr. Sara Dong @swinndong via #IDFellowCase #ID #Infectious Diseases #Infections #Differential
IDFellowCase #ID #Infectious ... Diseases #Infections ... Diagnosis #KSHV #HHV
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... CMV • EBV • HHV6 ... • Common clinical ... rav7ks #CNS #Infections
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation Kaposi sarcoma (KS): • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated ... predominance) • Clinical ... Light chain: - HHV8 ... and spleen • Clinical ... de Fremont #HHV8
IDSA Aspergillosis Treatment • Invasive pulmonary aspergillosis (IPA) • CNS aspergillosis • Cardiac Aspergillus infection •
Cardiac Aspergillus infection ... • Aspergillus infections ... of eye Infectious
Castleman's Disease and Associated Syndromes HYALINE VASCULAR VARIANT • unicentric, HHV8-ve, children and young. • Hyalinized vessels
• unicentric, HHV8 ... Plasmablastic subtype is HHV8 ... myeloma, POEMS) HHV8
Clinical spectrum of aspergillosis By Dr. Sara Dong @swinndong #ID #Infectious Diseases #Infections #Aspergillus #Aspergillosis #IA
Clinical spectrum ... swinndong #ID #Infectious ... Diseases #Infections
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