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diagnosis differential kaposi management rheumatology causes hhv kics comparison ddx diseases herpesvirus hivaids id idfellowcase infectious inflammatory lymphadenopathy microbiology sarcoma
KSHV Inflammatory Cytokine Syndrome (KICS) Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV Inflammatory ... 3) Evidence of KSHV ... Castleman disease ... if present Infectious ... diagnosis #management #hhv8
Kaposi Sarcoma Herpes Virus (KSHV) By Dr. Sara Dong @swinndong via #IDFellowCase #ID #Infectious Diseases #Infections #Differential
Herpes Virus (KSHV ... IDFellowCase #ID #Infectious ... Diseases #Infections ... Ddx #Diagnosis #KSHV ... #HHV #lymphoproliferative
Castleman's Disease and Associated Syndromes HYALINE VASCULAR VARIANT • unicentric, HHV8-ve, children and young. • Hyalinized vessels
Castleman's Disease ... • unicentric, HHV8 ... associated with Castleman's ... Plasmablastic subtype is HHV8 ... myeloma, POEMS) HHV8
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation Kaposi sarcoma (KS): • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated ... Light chain: - HHV8 ... + Multicentric Castleman ... de Fremont #HHV8 ... comparison #diagnosis #kshv
KSHV Inflammatory Cytokine Syndrome (KICS) By Dr. Sara Dong @swinndong via #IDFellowCase #ID #Infectious Diseases
KSHV Inflammatory ... IDFellowCase #ID #Infectious ... Diseases #Infections ... Ddx #Diagnosis #KSHV ... #HHV #KICS #Kaposi
Lymphadenopathy - Differential Diagnosis Algorithm Localized: • Cervical: EBV, CMV, HIV, Toxo, TB, Lymphoma, Head /
Melanoma • Axillary: Infection ... Sexually transmitted infections ... , Sjögren's • Infection ... Miscellaneous: Castleman's
Clinical Manifestations of Human Herpes Viruses (HHV) Herpes simplex virus 1 HSV-1 Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Herpes Viruses (HHV ... 20%) congenital infection ... herpes virus 6 HHV ... herpes virus 7 HHV ... herpesvirus 8 HHV
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
Preventing and Treating HHV ... , Multicentric Castleman ... activity against HHV ... KaposiSarcoma #Castlemans ... opportunistic #infections
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy Malignancies - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms Infections -
skin neoplasms Infections ... chancroid, cutaneous infections ... immunodeficiency virus, infectious ... node hyperplasia (Castleman
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 Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Acquired HLH: • Infections ... Virus (EBV, CMV, HHV8 ... Still disease, Infection ... Etiological+++: Anti-infectious
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