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diagnosis management algorithm classification polycythemia syndrome vasculitis acidosis adultonset capillary clarksons elevation hodgkins infectiousdiseases lactate lactic leak lymphoma mycobacteria nontuberculous
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
positive Family History ... Disease • Cyanotic ... Heart Disease ... Disease #Polycythemia ... #Hematology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Polycythemia - Acquired Causes ... Hypoxia-driven: Cardiac/pulmonary ... disease, Smoking ... Hypoxia-independent: Post-renal ... Diagnosis #Algorithm #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... • Systemic diseases ... autoinflammatory diseases ... AdultOnset #Stills #Disease ... #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... life-threatening diseases ... Inflammatory eye disease ... confirm DAH, r/o infection ... Goodpasture's cause
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Clarkson’s Disease ... - To treat disease ... - To prevent disease ... #Clarksons #Disease ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
disease, and ocular ... (Granulomatous disease ... atherosclerotic disease ... most important diseases ... #diagnosis #rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... , alcohol, cancer ... Hematologic malignancy ... History of immunosuppressive ... #differential #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Systemic rheumatic diseases ... atherosclerotic disease ... most important diseases ... (GRANULOMATOUS DISEASE ... #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... associated with other diseases ... demyelinating disease ... Tracheobronchial disease ... Sjogrens #Syndrome #Rheumatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... presentations and disease ... patient’s complete medical ... history - conduct ... output - Acute pulmonary
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