16 results
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
level. ... motor function, level ... #Syndromes #diagnosis ... pathophysiology #signs ... #symptoms #msk
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
(Composed of T-helper ... & inflammatory cells ... Constitutional: Fever ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
mutation) that alter ... /Symptoms: - Fever ... Anemia - Giant cells ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
levels, greater level ... less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... #rheumatology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
B and CD-4+ T cells ... -> Tissue injury ... Pancarditis and valvular injury ... pathophysiology #diagnosis ... #signs #symptoms
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
adults 20-30, older ... Differential Diagnosis ... Lymphomas • Other hematologic ... comparison #oncology #diagnosis ... #differential #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... patients 50 years or older ... constitutional symptoms ... #Significance #hematology ... #diagnosis #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... Lysis of tumor cells ... Syndrome #TLS #diagnosis ... #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Marrow (Toxic injury ... index < 2 • EPO Level ... • Improve the symptoms ... Anemia #oncology #hematology ... #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... tissue: Epithelioid cells ... at the time of diagnosis ... anterior/posterior MSK ... #Management #Signs