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Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) Absolute Insulin deficit: - Type I DM:
Ketoacidosis (DKA) and Hyperglycemic ... Hyperosmolar Syndrome ... Insulin demand: infections ... #ketoacidosis #hyperglycemic ... #hyperosmolar
Ketosis Disorders - Comparison Table • Starvation Ketosis • Alcoholic Ketoacidosis (AKA) • Diabetic Ketoacidosis (DKA)
Euglycemic DKA • Hyperglycemic ... Hyperosmolar State ... Disorders #ketones #differential
Anion Gap Metabolic Acidosis • Diabetic Ketoacidosis ± Hyperglycemia ± Hyperosmolar • Alcoholic Ketoacidosis ± Hyperglycemia
Ketoacidosis ± Hyperglycemia ... ± Hyperosmolar ... Ketoacidosis ± Hyperglycemia ... Metabolic #Acidosis #differential
Causes of Leukocytosis and Leukopenia - Differential Diagnosis • Eosinophilia (AEC > 500, hypereosinophilia > 1500):
and Leukopenia - Differential ... Connective Tissue, Infections ... Lymphocytosis: Infection ... Leukocytosis #Leukopenia #Differential ... Diagnosis #causes #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Pancytopenia - Differential ... Infiltration: • Hematologic ... and non-hematologic ... malignancies • Infection ... #Neutropenia #Differential
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - Differential ... deficiency) • Infection ... Sepsis • Non-infectious ... Thrombocytosis #Differential ... causes #Platelets #hematology
Quick review on streptococcal skin infections. Images from dermnet.nz #diagnosis #clinical #differential #dermatology #skinrash #skin
streptococcal skin infections ... #diagnosis #clinical ... #differential # ... dermatology #skinrash
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Myelofibrosis Infectious ... Non malignant hematologic ... states • Non-hematologic ... Thrombocytosis #Differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... • Nonmalignant hematologic ... : Chronic infections ... Thrombocytosis #Platelets #Differential
Approach to the Rash in a an oncology patient - MINT-C Mnemonic M - Malignancy: Leukemia cutis,
conditions I - Infection ... : Bacterial infections ... , Viral infections ... Rash #oncology #differential ... MINTC #Mnemonic #dermatology
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