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management hematology differential oncology syndrome neurology hemeonc mri hemophagocytic hlh lymphohistiocytosis tb tuberculosis activetb cardiology causes chronic cll cns heel
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... accumulation of clinical ... Acquired HLH: • Infections ... Still disease, Infection ... #summary #rheumatology
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
. tuberculosis infections ... inhibitors • Injection ... mycobacterial infection ... NTM) • Fungal infection ... unable to limit infection
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
cryoglobulinemia vasculitis - Diagnosis ... cryoglobulinemia vasculitis Clinical ... neuropathy Treatment ... related to HBV infection ... Cryoglobulinemia #Vasculitis #Rheumatology
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
. tuberculosis infections ... inhibitors • Injection ... mycobacterial infection ... NTM) • Fungal infection ... unable to limit infection
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Disseminated Infections ... pulmonary symptoms • Rheumatologic ... 50% in chronic infection ... has five major clinical ... fungal stain of clinical
Miliary Pattern - Chest Radiology • Miliary opacities are scattered, small (1 -4 mm) nodules •
Pattern - Chest Radiology ... Differential Diagnosis ... Nocardia, zoonotic infections ... #pulmonary #CXR ... #clinical #CT
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... common • Imaging: CXR ... : Infection (sepsis ... Renal Failure Treatment ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... can mimic common infections ... • Bicytopenia Treatment ... : • Infection ... #hematology
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
Syphilis - Clinical ... after initial infection ... with untreated infection ... after primary infection ... infection
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... Lung Abscess - Clinical ... Blood cultures • CXR ... early disease) • CXR ... hemorrhage • Treatment
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