25 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... auricular papules Clinical ... severity of the disease ... #rheumatology #dermatology ... #diagnosis
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Connective tissue disease ... #semiology #signs ... #lesions #diagnosis ... #clinical #manifestations
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... salmonella, ...), Parasites ... Drugs, Unknown cause
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
The signs and symptoms ... resembling rashes caused ... Syphilis #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
epidermis from dermis Clinical ... Signs/Symptoms/ ... - Erosions and crusts ... not feasible CMC ... #Management #dermatology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... years - May have signs ... intervention CMC
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess - Clinical ... : • CBC - Leukocytosis ... Coccidioides • Parasite ... #differential #causes
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... caused by the protozoan ... parasite Trypanosoma ... Romana's sign ... only available at CDC
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Framework Disease ... • CT: Halo sign ... factor • May cause ... possible in HIV PARASITIC ... #infectiousdiseases
Trypanosomiasis - Trypanosoma cruzi Life Cycle
1) Triatomine bug takes a blood meal (passes metacyclic trypomastigotes in
a blood meal (passes ... Clinical manifestations ... Tcruzi #LifeCycle #diagnosis ... pathophysiology #infectiousdiseases ... #cdc #parasite