19 results
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... Antibodies (MSAs ... , TIF1y, NXP2, Mi ... clinical #diagnosis #rheumatology ... #table
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... Associations ANA - Non-specific ... #diagnosis #table ... #rheumatology # ... antibodies
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
Tests for Celiac Disease ... patients with celiac disease ... as sensitive or specific ... value for celiac disease ... Diagnosis #Workup #Table
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... but often not specific ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... Association with disease ... with auto-immune diseases ... erythematosus #diagnosis #rheumatology ... #table #ANA
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... others (RNP, aPL antibodies ... , Others: SRP, Mi ... Autoantibodies #Rheumatology ... #associations #table
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... Specific inhibitors ... antiphospholipid antibodies ... antiphospholipid antibodies ... #differential #hematology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... and relapse No specific ... autoantibodies (antinuclear antibodies ... IgG4 #Related #Disease ... workup #treatment #rheumatology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antigen - Allergen-specific ... lgE antibodies ... When the specific ... during hemolytic disease ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... Action: Allergen-specific ... Action: IgG/lgM antibodies ... reaction, Haemolytic disease ... types #allergy #table