12 results
diagnosis differential hemolytic autoantibodies causes monoclonal oncology syndrome agglutinin aiha antibodies antinuclear autoimmune autoinflammatory behcet bodies comparison disorders e1 erythematosus
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic Anemia ... Differential Diagnosis Table ... AHA (16-32%) ... Agglutinin Disease ... #hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... connective tissue disease ... (TTG) - Celiac disease ... #diseases #diagnosis ... #table #rheumatology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
the population Disease ... Autoimmune diseases ... Lymphoproliferative diseases ... Insect stings Disease ... Urticaria #diagnosis #rheumatology
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
RBC Inclusions and ... Associations • ... , Hemolytic anemia ... : Hemoglobin H disease ... Bodies #diagnosis #hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
ULN R - Renal disease ... chain deposition disease ... lymphoproliferative diseases ... autoimmune diseases ... MGUS #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
agglutin disease ... e.g. sickle cell disease ... Hypersplenism, Wilson's disease ... differential #diagnosis #hematology ... #anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Disease 3 Types ... Agglutinin Disease ... • Autoimmune disease ... #agglutinin #disease ... #hematology #diagnosis
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Anti-dsDNA 60-80% Association ... with disease activity ... with auto-immune diseases ... erythematosus #diagnosis #rheumatology ... #table #ANA
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
alveolitis, ear and ... thromboembolic disease ... Abnormalities: macrocytic anemia ... myeloid cells NEJM ... Autoinflammatory #Somatic #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
PT, aPTT(liver disease ... function test, ANA ... changes), high MCV anemia ... bypass), LFT (liver disease ... Causes #Workup #hematology
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