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diagnosis hematology comparison differential management autoantibodies dermatomyositis syndrome activation acute antimda5 antimda5dm antinuclear antinxp2 antinxp2dm champs compared complement criteria dermatosis
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
with disease activity ... searched for when ANA ... #erythematosus ... #diagnosis #rheumatology ... #table #ANA
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... ANA (anti-nuclear ... , Others: SRP, Mi ... #diagnosis #associations ... #table
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... Inflammatory and ... : • Systemic lupus ... erythematosus ... Differential #Diagnosis #Hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Chain deposition disease ... S - Systemic Lupus ... Erythematosus ( ... Ann Marie Kumfer ... #differential #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... erythematosus ... erythematosus [ ... Diagnosis #Management #Hematology ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Erythematosus ( ... Workup: - ANA ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology #
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
associated with rheumatologic ... presentation of systemic lupus ... erythematosus. ... pain, such as MI ... Presentation #comparison #Table
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 ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
with edema • Erythematous ... severity of the disease ... frequently described Association ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
well-described associations ... presenting with erythematous ... Classic association ... Erythemas #comparison #table ... differential #diagnosis #dermatology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
onset of tender erythematous ... Association with ... inflammatory disease ... Criteria #Diagnosis #Hematology ... #Dermatology
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