13 results
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Anti-MDA5, anti-Mi ... Associated Features: Diagnosis ... #differential #diagnosis ... #comparison #rheumatology ... #table
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Rheumatology • ... , Others: SRP, Mi ... diagnosis #associations ... #table
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
, TIF1y, NXP2, Mi ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
Differentiating type-I vs. type-II MI

Sorting this out is difficult, often relying heavily on clinical judgement.

A key
relying heavily on clinical ... If the same symptoms ... The table below ... #Diagnosis #Myocardial ... NSTEMI #Comparison #Table
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... months) and of autoantibodies ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs/symptoms ... high index of clinical ... heart valves • MRI ... often seen • MRI ... #table
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... and duration of symptoms ... angioedema Other symptoms ... #rheumatology # ... comparison #table
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
associated with rheumatologic ... pain, such as MI ... #Pericarditis #Symptoms ... Presentation #comparison #Table ... #Diagnosis
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
-15% If SLE is clinically ... #Antinuclear #autoantibodies ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... in literature (NEJM ... cases (Cornelia NEJM ... them, but urgent rheumatology ... Temporal #Signs #Symptoms