12 results
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific Antibodies ... , TIF1y, NXP2, Mi ... #MSAs #clinical ... #diagnosis #rheumatology ... #table
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... others (RNP, aPL antibodies ... , Others: SRP, Mi ... #diagnosis #associations ... #table
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Inflammatory Myopathies ... Anti-MDA5, anti-Mi ... Pattern: Proximal and ... #comparison #rheumatology ... #table
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
diagnosis can only ... high index of clinical ... heart valves • MRI ... often seen • MRI ... #table
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Erythematosus Clinical ... least 2 joints • Neurologic ... Highly specific antibodies ... Erythematosus #diagnosis ... #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... -15% If SLE is clinically ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... bouts of HTN Diagnostic ... out compressive myelopathies ... Antiamphiphysin antibodies ... #management #neurology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... antibodies, which ... (to support a diagnosis ... and RF (if clinical ... #testing #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... in literature (NEJM ... cases (Cornelia NEJM ... them, but urgent rheumatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... - Metabolic myopathies ... Dermatomyositis Clinical ... per day until stable ... #Differential #Diagnosis