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diagnosis hematology management age apml bandemia causes coagulation dic differentiation dimer disseminated intravascular neutrophil oncology syndrome thromboticthrombocytopenicpurpura treatment ttp wbc
D-dimer Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
you perform age adjusted ... @DharSaty #Ddimer ... #dimer #pathophysiology ... #hematology #differential ... diagnosis #age #adjusted
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... 21% had normal WBC ... #Bandemia #differential ... #CBC #hematology ... #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Elevated D-Dimer ... protein C and S Pathophysiology ... • PTT: ↑ • D-Dimer ... hydration • RBC ... treatment #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... initiation • Differential ... QD until normal WBC ... diagnosis #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
products or D-dimer ... from ischemia WBC ... count and differential ... Diagnosis #Workup #Hematology
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