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diagnosis hematology algorithm management adjusted allergy apml asthma bandemia cbc classification common cvid ddimer ddxof dimer disorders humoral hypogammaglobulinemia immunity
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
) are produced from ... • Differentiation ... proliferate and differentiate ... Humoral #Immunity #pathophysiology ... #immunology
Asthma: immunopathogenesis. Allergens attach to, and are taken up by, dendritic cells that he the respiratory
attach to, and are ... cens leads to the differentiation ... B cells. which differentiate ... and release IgE ... immunopathogenesis #Pathophysiology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
impaired B-cell differentiation ... patients • Avg age ... IgA and/or IgM, age ... hypogammaglobulinemia #immunology ... #hematology #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation ... ATRA treatment Pathophysiology ... initiation • Differential ... nsrosenberg #Differentiation ... diagnosis #management #hematology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Pathophysiology: ... 1) If lesions are ... manifestations are ... #Diagnosis #Dermatology ... Palpable #Algorithm #Differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... - Bimodal Age ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
D-dimer Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
increase with age ... i.e. 80 yrs of age ... - Age (yrs) x 10 ... Ddimer #dimer #pathophysiology ... #hematology #differential
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Band neutrophils are ... Neutrophil (Normal) Differential ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
Multiple pricks are ... Pathergy #diagnosis #differential ... #allergy #immunology ... #dermatology #skin
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