17 results
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... - Bimodal Age ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
• Young age ... Asymptomatic, Age ... Non-Hodgkin's Lymphoma ... • Hodgkin's Lymphoma ... Algorithm #Causes #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
spleen or liver are ... Increases with age ... involvement Differential ... oncology #diagnosis #differential ... #hematology
Asthma: immunopathogenesis. 
Allergens attach to, and are taken up by, dendritic cells that he the respiratory
attach to, and are ... cens leads to the differentiation ... B cells. which differentiate ... and release IgE ... immunopathogenesis #Pathophysiology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
has a bimodal age ... in this group are ... Immunohistochemical studies (to differentiate ... abnormalities are ... classification #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation ... ATRA treatment Pathophysiology ... initiation • Differential ... nsrosenberg #Differentiation ... diagnosis #management #hematology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Pathophysiology: ... 1) If lesions are ... manifestations are ... #Diagnosis #Dermatology ... Palpable #Algorithm #Differential
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
) are produced from ... : Ag-presenting ... • Differentiation ... proliferate and differentiate ... Humoral #Immunity #pathophysiology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
impaired B-cell differentiation ... patients • Avg age ... hepatitis • Lymphoma ... IgA and/or IgM, age ... hypogammaglobulinemia #immunology #hematology
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Eosinophilia - Differential ... autoimmune): - Hyper IgE ... Primary: - CML - Lymphomas ... #Eosinophilia #Differential ... Diagnosis #Causes #hematology