43 results
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate
LOW PHOSPHATE
 - Low/NormaI PTH
Hypocalcemia - Differential ... Phenytoin, Nephrotic Syndrome ... ) • Calcium ... Poisoning #Hypocalcemia ... Algorithm #Phosphate #endocrinology
Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
Serum levels of PTH ... : - Hypoparathyroidism ... - Calcium-sensing ... Laboratory #Levels #Hyperparathyroidism ... #Diagnosis #Endocrinology
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
resorption: • Primary hyperparathyroidism ... histoplasmosis) • Milk (calcium ... )-alkali syndrome ... differential #diagnosis #calcium ... #high #endocrinology
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
: ↑→PTH, ↑Calcium ... : ↑PTH, ↓→Calcium ... : ↑↑PTH, ↑Calcium ... #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
Algorithm Primary Hyperparathyroidism ... Autosomal Dominant Calcium ... Malignancy • PTH-Related ... Other • Excess Calcium ... Diagnosis #Algorithm #Endocrinology
Multiple Endocrine Neoplasias (MEN syndromes) 

MEN I
• Hyperparathyroidism 
• Hypercalcemia 
• Possible ZE syndrome 
• Various
) MEN I • Hyperparathyroidism ... • Hypercalcemia ... Various Pituitary path ... • Hypercalcemia ... #Differential #Endocrinology
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
Parathyroid Hormone (PTH ... - Net Effect Hypercalcemia ... Parathyroid #Hormone #PTH ... #Phosphorus #pathophysiology ... #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Algorithm Elevated PTH ... normal): • Primary Hyperparathyroidism ... Low PTH: • Elevated ... Bony Mets - Calcium ... Algorithm #causes #endocrinology
Calcium Homeostasis

Serum Calcium - PTH - Vitamin D Regulation

#Calcium #Homeostasis #Pathophysiology #Autoregulation #VitaminD #PTH #Endocrinology
Serum Calcium ... - PTH - Vitamin ... #Homeostasis #Pathophysiology ... Autoregulation #VitaminD #PTH ... #Endocrinology
Hypocalcemia Workup - Differential Diagnosis Algorithm
 • Low Magnesium, High Magnesium - Functional Hypoparathyroidism
 • High
Hypocalcemia Workup ... Phosphate, Low PTH ... - Hypoparathyroidism ... Phosphate, High PTH ... metastases, Hungry bone syndrome