16 results
Hypocalcemia - Workup Algorithm

Dr Nikhil Lohiya - NEPHKIDS 2020 @NEPHKIDS1

#Hypocalcemia #Workup #Algorithm #differential #diagnosis #endocrinology #causes
Hypocalcemia - Workup ... #Workup #Algorithm ... #differential # ... diagnosis #endocrinology ... #causes #calcium
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
histoplasmosis) • Milk (calcium ... )-alkali syndrome ... #Causes #differential ... #diagnosis #calcium ... #high #endocrinology
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential ... #Workup #Differential ... Diagnosis #algorithm #endocrinology ... #calcium
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... hyperuricemia, #hyperkalemia ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS ... #Workup #tumorlysissyndome
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Hypercalcemia Evaluation ... #workup #differential ... #diagnosis #endocrinology ... #calcium #elevated ... #evaluation #workup
Hypocalcemia Workup - Differential Diagnosis Algorithm
 • Low Magnesium, High Magnesium - Functional Hypoparathyroidism
 • High
Hypocalcemia Workup ... - Differential ... deficiency • Drugs: Calcium ... metastases, Hungry bone syndrome ... #Workup #Differential
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... leukapheresis - TLS ... : • Pathophysiology ... hydration - Hyperkalemia ... #TLS #diagnosis
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... - Calcium Sequestration ... - DiGeorge Syndrome ... Diagnosis #Management #endocrinology ... #differential #
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate
LOW PHOSPHATE
 - Low/NormaI PTH
Hypocalcemia - Differential ... Phenytoin, Nephrotic Syndrome ... Poisoning #Hypocalcemia ... #Differential # ... Algorithm #Phosphate #endocrinology
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
Causes of Hypercalcemia ... Lithium use • Calcium-sensing ... • Milk-alkali syndrome ... #Causes #endocrinology ... #diagnosis #differential