30 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Syndrome Signs/Symptoms ... delayed puberty -> Infertility ... sleep apnea, cor pulmonale ... pathophysiology #peds #pediatrics
Osteosarcoma 
Most common primary malignant bone tumor in children 
Most Common Sites of Involvement:
1. Distal femur
proximal femur Clinical ... injury • Systemic symptoms ... #Osteosarcoma #Diagnosis ... #Features #Oncology ... #Peds #Pediatrics
Lung Abscess
Microbiology:
 • Polymicrobial 
 • Anaerobes (most common) 
Clinical: 
 • Indolent symptoms that evolve
most common) Clinical ... • Indolent symptoms ... , hemoptysis Treatment ... Lung #Abscess #Diagnosis ... #Pulmonary #Clinical
Diagnostic Algorithm for Suspected Pulmonary Embolism

Well's Criteria for PE
 • Clinical Signs and Symptoms of DVT
Diagnostic Algorithm ... for Suspected Pulmonary ... Criteria for PE • Clinical ... Signs and Symptoms ... #Algorithm #WellsCriteria
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology ... hematology #hemeonc #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... : >3 symptoms, or ... Renal Failure Treatment ... management #hematology #oncology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... for alternate diagnoses ... of AECOPD: • Clinical ... #Exacerbation #treatment ... #pulmonary
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
acute respiratory symptoms ... symptoms • Rheumatologic ... symptoms • Pericarditis ... has five major clinical ... fungal stain of clinical
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... → no immediate treatment ... renal failure, pulmonary ... #Emergencies #Oncology ... #HemeOnc #Diagnosis
Algorithm for the Diagnosis of Serotonin Syndrome
 - Serotonin syndrome is thought to be caused by
Algorithm for the ... Diagnosis of Serotonin ... - Clinical findings ... initiation of treatment ... #Symptoms