14 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... cases, drug-dependent ... Lupusreference #druginduced ... #lupus #sle #comparison
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Headache, Movement disorders ... , Seizure disorders ... autoantibodies that will cause ... Erythematosus #SLE
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
duration), Several medications ... /HDS treatments ... for alternative causes ... Hepatic vascular disorder ... hepatitis #DILI #DrugInduced
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Lupus Erythematosus ... SLE High risk ... for 1 year of treatment ... Lupusreference #DrugInduced ... #medications #drugs
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
disease (MCTD), Drug-induced ... Lymphoproliferative Disorders ... Biliary Cirrhosis, Drug-Induced ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... Arthritis • SLE ... Chronic Obstructive Pulmonary ... • Somatization Disorder
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm INDICATIONS ... asthma, allergy, drug ... glucocorticoid treatment ... Differential #diagnosis #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Malignancy (e.g. hematologic ... extremities Drug ... • Antihistone: Drug ... activation and/or medications
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
Temp • ACS • Drugs ... Hyperkalemia Pulmonary ... • Congenital disorders ... Heart block Medications ... Autoimmune: • SLE
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... cases, drug-dependent ... is rare in DIL, SCLE-DIL ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology