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VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... Syndrome: • Common Clinical ... vasculitis • Hematologic ... criteria for 1) hematologic ... and/or 2) Inflammatory
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
background of a highly inflammatory ... release of pro-inflammatory ... fever syndromes Clinical ... Fever is the main clinical ... Diagnosis #Management #Hematology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Pathogenesis and clinical ... findings • Inflammatory ... anti-coagulation • Hematologic
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
(COVID-19) • Inflammatory ... Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
rituximab (in clinical ... related: raised inflammatory ... Complications #diagnosis #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Gastrointestinal inflammatory ... hypogammaglobulinemia #immunology #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... abnormalities • Inflammatory ... likelihood of negative clinical ... neutrophil #WBC #CBC #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Acute or Chronic Inflammatory ... Non malignant hematologic ... states • Non-hematologic ... Algorithm #Causes #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... or low • ESR (Inflammatory ... Reed-Sternberg cells and inflammatory ... classification #hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
coagulation (DIC) INFLAMMATORY ... APLS:PLT ↓ HEMATOLOGIC ... Diagnosis #clots #hematology
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