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diagnosis differential clinical algorithm dermatology management causes physicalexam rheumatology video hepatology photo treatment pathophysiology neurology skinrash table ucsdh nephrology cardiology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... myelosuppressive agents • Inflammatory ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... vasculitis • Hematologic ... criteria for 1) hematologic ... and/or 2) Inflammatory ... Autoinflammatory #Somatic #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Wiskott-Aldrich syndrome ... • Lymphoma Inflammatory ... Differential #Diagnosis #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
hemorrhage) • Chronic inflammatory ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Criteria for Sweet Syndrome ... an underlying hematologic ... malignancy, inflammatory ... neutrophils #Sweet #Syndrome ... Criteria #Diagnosis #Hematology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Candidiasis Inflammatory ... arthritis - Inflammatory ... Seronegative Reactive Syndrome ... Effusions: - Hematologic ... Osteochondroma Hematologic
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... Autoimmune / Inflammatory ... Chronic Fatigue Syndrome
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... background of a highly inflammatory ... release of pro-inflammatory ... Diagnosis #Management #Hematology ... #Rheumatology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Lemierre's syndrome ... Malignancy: - Hematologic ... Non-infectious Inflammatory
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Gastrointestinal inflammatory ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
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