1020 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... myelosuppressive agents • Inflammatory ... Kawasaki, Nephrotic syndrome ... Thrombocytosis #Platelets #Differential
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... Wiskott-Aldrich syndrome ... • Lymphoma Inflammatory ... #Pancytopenia #Differential ... #Diagnosis #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... hemorrhage) • Chronic inflammatory ... Myelodysplastic syndrome ... Thrombocytosis #Differential ... Diagnosis #Causes #hematology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue - Differential ... Neoplastic / Hematologic ... Autoimmune / Inflammatory ... Chronic Fatigue Syndrome ... Chronic #Fatigue #Differential
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Candidiasis Inflammatory ... arthritis - Inflammatory ... Seronegative Reactive Syndrome ... Effusions: - Hematologic
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Origin (FUO) - Differential ... Lemierre's syndrome ... Malignancy: - Hematologic ... Non-infectious Inflammatory ... #Origin #FUO #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
photosensitivity, inflammatory ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... Shrinking lung syndrome ... vein thrombosis Hematologic
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic Inflammatory ... Antisynthetase Syndrome ... TerrierBen #Inflammatory ... Managment #algorithm #Rheumatology ... #Differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Acute or Chronic Inflammatory ... Non malignant hematologic ... states • Non-hematologic ... Thrombocytosis #Differential
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... Hypereosinophilic Syndrome ... suspect underlying hematologic ... Hypereosinophilic #Syndrome ... #HES #Hematology