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Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Causes include : ... Pre-analytical cause ... Inhibitors: Non ... specific inhibitor ... aPTT #Prolonged #Causes
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Direct Xa inhibitors ... Specific inhibitors ... Pre-analytical cause ... aPTT #Prolonged #Causes
Treatment Options for Helicobacter Pylori and Peptic Ulcer Disease

Active Helicobacter pylori—associated ulcer
1. Treat with anti—H pylori
• Proton pump inhibitor ... • Proton pump inhibitor ... • Proton pump inhibitor ... Consider other causes ... • Proton pump inhibitors
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Extrarenal Proton pump inhibitor ... Tyrosine kinase inhibitors ... - Calcineurin inhibitors ... diagnosis #nephrology #Causes
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... Hypovolemia • RAAS inhibitor ... • Calcineurin inhibitor ... Differential #Diagnosis #Causes
Common causes of post-Transplant Diarrhea
 • Bacterial: Clostridium difficile, Campylobacter spp., Salmonella spp., Bacterial overgrowth, Aeromonus
Common causes of ... Laxatives, Proton pump inhibitors ... , Protease inhibitors ... #differential #causes
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... Mechanisms of Action: Inhibits ... not definitively cause ... featured #DPP4 #Inhibitors
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Deficiency or an inhibitor ... clotting factor inhibitors ... - factor VIII inhibitor ... )* • Acquired inhibitor ... discern these causes
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
The Inhibited Pathway ... caused by N2O, ... are due to its inhibition ... the irreversible inhibition ... use of N2O can cause
Polyuria - Differential Diagnosis
Solute Diuresis
 • Na intake/saline
 • Glucosuria: Hyperglycemia, SGLT-2 inhibitors
 • Urea: Exogenous
Hyperglycemia, SGLT-2 inhibitors ... Differential #Diagnosis #Causes