11 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... Renal Failure Treatment ... • Supportive Care ... diagnosis #management #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Reactive Syndrome - Acute ... Effusions: - Hematologic ... #diagnosis #msk ... #physicalexam
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
: • Acute or chronic ... e.g., congenital hip ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... spine, shoulders, hips ... Joint #pain #Differential ... #Diagnosis #MSK ... #rheumatology #
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Lung Disease - Differential ... Primary - Other (Rare ... Disease - Rheumatoid Arthritis ... , Beomycin • Acute ... Amy Chung, MD, MSc
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... Responsive to Treatment ... Treated Like Acute ... Amy Chung, MD, MSc ... pathophysiology #Hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Like in this case ... - parvovirus, HIV ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Herpes zoster - HIV ... Immobilization) • Acute ... lower #extremity #msk ... #physicalexam
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
are dysfunctional ... Agent Orange or Hep ... microglobulin Treatment ... ’s lymphoma or acute ... workup #oncology #hematology
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
hip muscle groups ... presents with an acute ... hips ... for giant cell arteritis ... help differentiate