11 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
granules which are ... during an allergic reaction ... translocation • Acute ... thrombocythemia • Acute ... #hematology #basophils
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... = nonspecific (nausea ... Diagnosis: Viral Hepatitis ... Support - Critical care ... Liver #Pregnancy #hepatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... transformation to acute ... Conservative/supportive care ... #treatment #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... subclinical disease to acute ... (eg Viral) Management ... AIH #Diagnosis #Management ... #Hepatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... Causes purpura & ... Transfusion Related Acute ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Causes purpura & ... Transfusion Related Acute ... Transfusions #diagnosis #management ... #hematology #reactions
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... normal in mild cases ... severity Treatment - Acute ... Chronic Management ... #treatment #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... NT) - If both are ... Chronic viral hepatitis ... liver #injury #hepatitis ... diagnosis #algorithm #hepatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Liver diseases and hepatitis ... and M panel Management ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... exclude other causes ... Treatment: - Acute ... #hepatology