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diagnosis oncology treatment differential mds myelodysplastic algorithm anemia aplastic apml bleeding bruising calcium cancer cardiology chestpain chronic cll cppd deposition
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... leukemia Management ... Conservative/supportive care ... #treatment #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... develop leukostasis syndrome ... • Tumor lysis syndrome ... When Cancer Cells are ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
large numbers and are ... ’s lymphoma or acute ... • Sezary syndrome ... #diagnosis #workup ... #oncology #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
• Supportive care ... progress to MDS or acute ... leukemia • Associated ... Anemia #diagnosis #management ... #treatment #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Supportive Care ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Workup: • Complete ... #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... presents as an acute ... insulting agent are ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
HEART Score – A Tool For the ED The HEART score is an excellent tool that
with possible Acute ... Coronary Syndrome ... admission for further workup ... offer appropriate care ... #Diagnosis #Management
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
gingivitis or gingival leukemic ... von Willebrand syndrome ... • Warfarin • Acute ... Liver disease • Acute ... Differential #Diagnosis #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... gastric tumors • Hematology ... : Lymphoma, Leukemia ... differential #diagnosis #hematology
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